Protein Info for GFF3477 in Pseudomonas sp. DMC3

Annotation: Methyl-accepting chemotaxis protein McpH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 663 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 310 to 330 (21 residues), see Phobius details PF22673: MCP-like_PDC_1" amino acids 98 to 200 (103 residues), 32.1 bits, see alignment E=2.7e-11 PF02743: dCache_1" amino acids 125 to 293 (169 residues), 53.7 bits, see alignment E=4.5e-18 PF00672: HAMP" amino acids 330 to 381 (52 residues), 31 bits, see alignment 5.3e-11 PF00015: MCPsignal" amino acids 473 to 627 (155 residues), 137.8 bits, see alignment E=7e-44

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 95% identity to pfo:Pfl01_2554)

Predicted SEED Role

"Methyl-accepting chemotaxis protein III (ribose and galactose chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (663 amino acids)

>GFF3477 Methyl-accepting chemotaxis protein McpH (Pseudomonas sp. DMC3)
MPALRTIQARYTLFLILFILLLSVLTVVGISQLVAPTLRDTEEKVVLNRIAEVAVQIQGE
LNKVQAQQRSITQTIPLLDSAAIDVVLPGLVDQYGELKVFGGGIWPLPGQREAGRNKFST
FWHRDASGQLKVNTFWNSDAAPNYYDQSWHKGGMATPRGQCAWAAAYKDDASAEPRTNCA
MAIYKNGSAWGVSTIDVTLGFFNDLVARKEKDLNAEMLIVEADGKIISNSSRISGPIVLK
NISELAASSTFINQIKTGLQNRDKAQRVEFDNNGEDATFFMRPIEGTPWFLATALPTKML
TAQRDDVLNSLSLIQIPLVILLVLLQVYAIRKLVQRMKALKANIDSLSSGDADLTRRITI
RAEDELGAIGHSVNTFIVYLQNMIGEVTQATGAMASSLDNLQRTSAHTSQILLRHASETD
QTVTAITEMSSTAESVAQNAAETAAFTQRANENADRSRVVVGEATNSVVALIDEVASATH
KVENMQQDAQRITEILGVIGAIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAAR
TQASTSEINEMLTRLTQGVSSSVSAMENTQASCQSAADATARVNSGLDEMAGSVSHINSL
STQIATAAEQQSAVTEEINRSMVQIRHMVDELVQSGQASELNTRQLLEANSRVSAIMGRF
KVS