Protein Info for GFF3462 in Xanthobacter sp. DMC5

Annotation: ATP-dependent RNA helicase RhlE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 570 PF04851: ResIII" amino acids 48 to 214 (167 residues), 31.3 bits, see alignment E=2.7e-11 PF00270: DEAD" amino acids 50 to 220 (171 residues), 168.1 bits, see alignment E=2.1e-53 PF00271: Helicase_C" amino acids 256 to 364 (109 residues), 107.6 bits, see alignment E=6.4e-35

Best Hits

KEGG orthology group: None (inferred from 77% identity to xau:Xaut_3204)

Predicted SEED Role

"ATP-dependent RNA helicase RhlE" in subsystem ATP-dependent RNA helicases, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (570 amino acids)

>GFF3462 ATP-dependent RNA helicase RhlE (Xanthobacter sp. DMC5)
MSKSREPRRAQKAAPVPLAYESQSLTSFSSLGLAEPIVRALTEANHVTPTPIQAEAIPQV
LAGRDLIGIAQTGTGKTAAFALPILDRLVRHPRRPDPKSVRALVLSPTRELSGQIVDNFE
KFGRHARISVTLAIGGVPMGRQIRALARGVDVLVATPGRLMDLVENHAVKLDQVEVLVLD
EADQMLDMGFVHAIRAIVRRLPHKRHSLFFSATMPPAIAELAGGMLHDPVRVAVTPVAKT
ADRVEQRVIHVDKPNKGQLLAEVLSTEEIDRALVFARTKHGADKVVRVLAKCGIAAEAIH
GNKSQNQRDRVLLAFREGKIRTLIATDIAARGIDVTGVSHVINYDLPNVPESYVHRIGRT
ARAGREGIAISFCDHEERAYLKSIERLIKLQIPATDRRGAGMRFAIPDAPPIELEERDET
AERNDFIGGRGGRPGQRGPQRSRGPRPEGREGGRGQGQRAEGREQREPRGERPAGEGRPA
RAAQPRPERAPEGHRNAQGAGNGAGRRDGQNRSGEGRGARPQGEGRGGERGGDRGARPGN
DLGGLGFMKAVSNRSERPAGRPAGAKRPVN