Protein Info for GFF3432 in Variovorax sp. SCN45

Annotation: L-carnitine dehydratase/bile acid-inducible protein F

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02515: CoA_transf_3
  • amino acids 8 to 389 (382 residues), 435.4 bits, E=9.1e-135

Best Hits

KEGG orthology group: None (inferred from 96% identity to vpe:Varpa_0131)

MetaCyc: 59% identical to succinyl-CoA-glutarate CoA-transferase (Pseudomonas putida)
Succinate--hydroxymethylglutarate CoA-transferase. [EC: 2.8.3.13]

Predicted SEED Role

"L-carnitine dehydratase/bile acid-inducible protein F"

MetaCyc Pathways

• L-lysine degradation X (4/6 steps found)
• L-lysine degradation IV (2/5 steps found)
• superpathway of L-lysine degradation (12/43 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.8.3.13

Protein Sequence (412 amino acids)

>GFF3432 L-carnitine dehydratase/bile acid-inducible protein F (Variovorax sp. SCN45)
MNKPAAALDGIKVLDLSRVLAGPWCTQILADLGADVVKIERPGVGDDTRTWGPPFIKDAD
GNDTDQASYFTACNRNKRSVTVDMATPEGQALLRQMAAQADIVVENFKTGGLKQYGLDQE
SLRAANPRLIYCSVTGFGHDGPYAERAGYDLMIQAMTGMMSITGRPDDVPGGGPLRVGVA
LTDLFTGVYASTAILAALQVRDRTGEGQHIDMALLDVGMAILANQASAFLNTGKAPGRQG
NTHPSLAPYQDFPTQDGAMLLAIGNNGQFARFCEAGGHPEWASDARFATNTLRVKHRGVL
IPMMEELTRTRTTAAWVTLLEDKAVPCGPINDIAQAFDDAQVQARGLKVTLPRDAGDGIA
SIAGVASPLRLSATPPVLRHAPPALGQHTREVLAEMGIDDARFDALRSAGVV