Protein Info for GFF3420 in Xanthobacter sp. DMC5

Annotation: Oligopeptide-binding protein AppA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 signal peptide" amino acids 1 to 41 (41 residues), see Phobius details PF00496: SBP_bac_5" amino acids 96 to 458 (363 residues), 314.6 bits, see alignment E=5e-98

Best Hits

KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 79% identity to azc:AZC_2659)

Predicted SEED Role

"Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) or Sex pheromones in Enterococcus faecalis and other Firmicutes (TC 3.A.1.5.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (547 amino acids)

>GFF3420 Oligopeptide-binding protein AppA (Xanthobacter sp. DMC5)
MAPPADAVPSLASRPRRAVLKGLLAAACVLGAAAAAPVWAADAQSTPQPVRGGVLRFLVE
HEPSTLVSIAHTAGPTQRVSPKVTEGLLAYDLDFNPKPALATEWSVSPDGLTYTFKLREG
VKWHDGRDFTADDVAYSIQLLKEGHPRGRATFASVTAVETPDPHTAIIRLSKPAPYLLTA
LDANESPIVAKHIYAGTDPLTNKNGAAPIGTGPFLFKEWVRGSHIILERNPDYWDADKPY
LDRVVVRFIADQSARAAAFETGELDLAGGPPVPRSDLARVQALPNLGSETRGYEYNGNMT
QLYFNFDTPQLKDKRVRLAIAQALDLNKLLDVVYFGYGTIAPSPVGPDLKKFVDPSIKPY
PFDLKAANRLLDEAGYPRKADGTRFALRLYANPFNGRESGDFVKQALAKVGIPVDFQFFD
FSTYIQKAYTGREFDLTLESLSNTFDPTPGIQRIFWSKNFKIGLPFSNASHYDNPQVDAL
LEAGAVESDPEKRRQIWFAFQKAIHDDVAAVHLIAPQGVTIFNKKVKNHTLGVTGPNASF
ADVWIEK