Protein Info for GFF334 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Mg(2+) transport ATPase, P-type (EC 3.6.3.2)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 908 transmembrane" amino acids 86 to 105 (20 residues), see Phobius details amino acids 117 to 134 (18 residues), see Phobius details amino acids 294 to 315 (22 residues), see Phobius details amino acids 324 to 348 (25 residues), see Phobius details amino acids 715 to 753 (39 residues), see Phobius details amino acids 777 to 800 (24 residues), see Phobius details amino acids 812 to 830 (19 residues), see Phobius details amino acids 842 to 862 (21 residues), see Phobius details amino acids 876 to 895 (20 residues), see Phobius details TIGR01524: magnesium-translocating P-type ATPase" amino acids 18 to 907 (890 residues), 1657.1 bits, see alignment E=0 PF00690: Cation_ATPase_N" amino acids 34 to 98 (65 residues), 63.5 bits, see alignment 3e-21 PF00122: E1-E2_ATPase" amino acids 149 to 357 (209 residues), 128.5 bits, see alignment E=5.4e-41 TIGR01494: HAD ATPase, P-type, family IC" amino acids 274 to 411 (138 residues), 67.2 bits, see alignment E=9.7e-23 amino acids 617 to 737 (121 residues), 101.9 bits, see alignment E=3e-33 PF00702: Hydrolase" amino acids 373 to 662 (290 residues), 55.6 bits, see alignment E=2.5e-18 PF13246: Cation_ATPase" amino acids 423 to 486 (64 residues), 23.2 bits, see alignment 1.4e-08 PF00689: Cation_ATPase_C" amino acids 731 to 899 (169 residues), 80.1 bits, see alignment E=4.6e-26

Best Hits

Swiss-Prot: 100% identical to ATMB_SALTY: Magnesium-transporting ATPase, P-type 1 (mgtB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01531, Mg2+-importing ATPase [EC: 3.6.3.2] (inferred from 72% identity to esa:ESA_pESA3p05536)

Predicted SEED Role

"Mg(2+) transport ATPase, P-type (EC 3.6.3.2)" (EC 3.6.3.2)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.2

Use Curated BLAST to search for 3.6.3.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (908 amino acids)

>GFF334 Mg(2+) transport ATPase, P-type (EC 3.6.3.2) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MTDMNIENRKLNRPASENDKQHKKVFPIEAEAFHSPEETLARLNSHRQGLTIEEASERLK
VYGRNEVAHEQVPPALIQLLQAFNNPFIYVLMALAGVSFITDYWLPLRRGEETDLTGVLI
ILTMVSLSGLLRFWQEFRTNRAAQALKKMVRTTATVLRRGPGNIGAVQEEIPIEELVPGD
VVFLAAGDLVPADVRLLASRDLFISQSILSGESLPVEKYDVMADVAGKDSEQLPDKDKSL
LDLGNICLMGTNVTSGRAQAVVVATGSRTWFGSLAKSIVGTRTQTAFDRGVNSVSWLLIR
FMLIMVPVVLLINGFSKGDWVEASLFALAVAVGLTPEMLPMIVSSNLAKGAIAMSRRKVI
VKRLNAIQNFGAMDVLCTDKTGTLTQDNIFLEHHLDVSGVKSSRVLMLAWLNSSSQSGAR
NVMDRAILRFGEGRIAPSTKARFIKRDELPFDFVRRRVSVLVEDAQHGDRCLICKGAVEE
MMMVATHLREGDRVVALTETRRELLLAKTEDYNAQGFRVLLIATRKLDGSGNNPTLSVED
ETELTIEGMLTFLDPPKESAGKAIAALRDNGVAVKVLTGDNPVVTARICLEVGIDTHDIL
TGTQVEAMSDAELASEVEKRAVFARLTPLQKTRILQALQKNGHTVGFLGDGINDAPALRD
ADVGISVDSAADIAKESSDIILLEKDLMVLEEGVIKGRETFGNIIKYLNMTASSNFGNVF
SVLVASAFIPFLPMLAIHLLIQNLMYDISQLSLPWDKMDKEFLRKPRKWDAKNIGRFMLW
IGPTSSIFDITTFALMWYVFAANNVEAQALFQSGWFIEGLLSQTLVVHMLRTQKIPFIQS
RATLPVLLTTGLIMAIGIYIPFSPLGAMVGLEPLPLSYFPWLVATLLSYCLVAQGMKRFY
IKRFGQWF