Protein Info for GFF3316 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: XdhC protein (assists in molybdopterin insertion into xanthine dehydrogenase)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 283 transmembrane" amino acids 35 to 56 (22 residues), see Phobius details PF02625: XdhC_CoxI" amino acids 13 to 73 (61 residues), 54.9 bits, see alignment E=6.9e-19 TIGR02964: xanthine dehydrogenase accessory protein XdhC" amino acids 18 to 270 (253 residues), 271.8 bits, see alignment E=2.8e-85 PF13478: XdhC_C" amino acids 123 to 269 (147 residues), 117.2 bits, see alignment E=6.9e-38

Best Hits

KEGG orthology group: K07402, xanthine dehydrogenase accessory factor (inferred from 64% identity to aav:Aave_1118)

Predicted SEED Role

"XdhC protein (assists in molybdopterin insertion into xanthine dehydrogenase)" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (283 amino acids)

>GFF3316 XdhC protein (assists in molybdopterin insertion into xanthine dehydrogenase) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MLSDLEAFLLRLATERAVLVTVGATRGSVPRETGAWMAVFAGAAGGAVGTIGGGHLEWDA
MRHAREALGRGAAERFAPWSQAVTLGPSLGQCCGGALVLHFEPVDASCREALRRRLTHGH
APLALFGGGHVGRALVQALAPLPFDVTWIDSRDEVFPHDLPPSVRTEYSEPVQLAVRDLA
PRSSVLIMSFSHAEDLDIVAACLQRQRQHGDLGFVGLIGSKTKWATFRRRLRQRGFSEAE
LSRITCPIGLPGIQGKAPAVIAASVVAQLLLVCETTSDAHLTS