Protein Info for GFF3292 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Secreted protein, suppressor for copper-sensitivity ScsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF13462: Thioredoxin_4" amino acids 44 to 198 (155 residues), 65.2 bits, see alignment E=1.7e-21 PF13098: Thioredoxin_2" amino acids 51 to 198 (148 residues), 43.7 bits, see alignment E=6.2e-15 PF01323: DSBA" amino acids 57 to 195 (139 residues), 94.6 bits, see alignment E=1.4e-30

Best Hits

KEGG orthology group: None (inferred from 97% identity to stt:t1805)

Predicted SEED Role

"Secreted protein, suppressor for copper-sensitivity ScsC" in subsystem Copper homeostasis: copper tolerance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (207 amino acids)

>GFF3292 Secreted protein, suppressor for copper-sensitivity ScsC (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MKYMIVLLLALFSTLSIAQETAPFTPDQEKQIENLIHAALFNDPASPRIGAKHPKLTLVN
FTDYNCPYCKQLDPMLEKIVQKYPDVAVIIKPLPFKGESSVLAARIALTTWREHPQQFLA
LHEKLMQKRVYHTDDSIKQAQQKAGATPVTLDEKSMETIRTNLQLARLVGVQGTPATIIG
DELIPGAVPWDTLEAVVKEKLASANGG