Protein Info for GFF3289 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: DnaJ-class molecular chaperone CbpA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 PF00226: DnaJ" amino acids 5 to 66 (62 residues), 85.3 bits, see alignment E=2.4e-28 PF01556: DnaJ_C" amino acids 120 to 276 (157 residues), 138.6 bits, see alignment E=1.8e-44

Best Hits

Swiss-Prot: 100% identical to CBPA_SALA4: Curved DNA-binding protein (cbpA) from Salmonella agona (strain SL483)

KEGG orthology group: K05516, curved DNA-binding protein (inferred from 100% identity to sec:SC1063)

Predicted SEED Role

"DnaJ-class molecular chaperone CbpA" in subsystem Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (306 amino acids)

>GFF3289 DnaJ-class molecular chaperone CbpA (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQ
RRAEYDQLWQHRNDPQFNRQFQQHEGQPYNAEDFDDIFSSIFGQHGRHSHHRHAARGHDI
EIEVAVFLEETLEEHQRTISYSVPVYNAFGLVEREIPKTLNVKIPAGVSNGQRIRLKGQG
TPGENGGPNGDLWLVIHIAPHPLFDIVNQDLEVVLPLAPWEAALGAKVSVPTLKERILLT
IPPGSQAGQRLRIKGKGLASKKHTGDLYAIIKIVMPPKPDEKTAALWQQLADAQSSFDPR
QQWGKA