Protein Info for GFF3273 in Variovorax sp. SCN45

Annotation: Translation initiation factor 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 311 transmembrane" amino acids 136 to 158 (23 residues), see Phobius details PF13240: Zn_Ribbon_1" amino acids 5 to 25 (21 residues), 28 bits, see alignment (E = 7.2e-11)

Best Hits

KEGG orthology group: None (inferred from 63% identity to vpe:Varpa_6017)

Predicted SEED Role

"Translation initiation factor 2" in subsystem NusA-TFII Cluster or Translation initiation factors eukaryotic and archaeal or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (311 amino acids)

>GFF3273 Translation initiation factor 2 (Variovorax sp. SCN45)
MALICPVCSTENRDGANFCRSCGNTLSGKATRIPPPPSPEREWATTAPAQLRAPTIPAPL
FDPGELEPRRSFFGRSSAPAPSDDQETMIMVYDDPPPPPPPAPSSGFETARQEKAERKRT
RVKVRRPVERPPRKRVILLWLGLLAVAVLMMVAGWYGYGTRKAPAAITDTEPAVSAPAVE
PAAPPAEPASPPAPAAPEPPAAEAPPAAEAAPLAASAKPPARPRKQATVAAPATGTPETP
APAVAAAPPPPAPAPPPPEPLAQCGDRNFIARAQCMAAQCLKAEYKAHAQCEAVRRQQRI
DEEKRNPTLIN