Protein Info for GFF3268 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868
Annotation: Inositol phosphate phosphatase sopB (EC 3.1.3.-)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to SOPB_SALTY: Inositol phosphate phosphatase SopB (sopB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG orthology group: K13085, phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC: 3.1.3.78] (inferred from 100% identity to seh:SeHA_C1201)MetaCyc: 100% identical to inositol phosphate phosphatase sopB (Salmonella enterica)
3.1.3.-
Predicted SEED Role
"Inositol phosphate phosphatase sopB (EC 3.1.3.-)" (EC 3.1.3.-)
MetaCyc Pathways
- D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis (1/4 steps found)
- D-myo-inositol-5-phosphate metabolism (1/4 steps found)
- 3-phosphoinositide degradation (1/9 steps found)
- superpathway of inositol phosphate compounds (2/26 steps found)
KEGG Metabolic Maps
- Aminosugars metabolism
- Ascorbate and aldarate metabolism
- Ether lipid metabolism
- Fructose and mannose metabolism
- Lipopolysaccharide biosynthesis
- Nicotinate and nicotinamide metabolism
- Riboflavin metabolism
- Sphingolipid metabolism
- Thiamine metabolism
Isozymes
Compare fitness of predicted isozymes for: 3.1.3.-
Use Curated BLAST to search for 3.1.3.- or 3.1.3.78
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (561 amino acids)
>GFF3268 Inositol phosphate phosphatase sopB (EC 3.1.3.-) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868) MQIQSFYHSASLKTQEAFKSLQKTLYNGMQILSGQGKAPAKAPDARPEIIVLREPGATWG NYLQHQKASNHSLHNLYNLQRDLLTVAATVLGKQDPVLTSMANQMELAKVKADRPATKQE EAAAKALKKNLIELIAARTQQQDGLPAKEAHRFAAVAFRDAQVKQLNNQPWQTIKNTLTH NGHHYTNTQLPAAEMKIGAKDIFPSAYEGKGVCSWDTKNIHHANNLWMSTVSVHEDGKDK TLFCGIRHGVLSPYHEKDPLLRHVGAENKAKEVLTAALFSKPELLNKALAGEAVSLKLVS VGLLTASNIFGKEGTMVEDQMRAWQSLTQPGKMIHLKIRNKDGDLQTVKIKPDVAAFNVG VNELALKLGFGLKASDSYNAEALHQLLGNDLRPEARPGGWVGEWLAQYPDNYEVVNTLAR QIKDIWKNNQHHKDGGEPYKLAQRLAMLAHEIDAVPAWNCKSGKDRTGMMDSEIKREIIS LHQTHMLSAPGSLPDSGGQKIFQKVLLNSGNLEIQKQNTGGAGNKVMKNLSPEVLNLSYQ KRVGDENIWQSVKGISSLITS