Protein Info for GFF3260 in Variovorax sp. SCN45

Annotation: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 503 PF01546: Peptidase_M20" amino acids 107 to 486 (380 residues), 71.3 bits, see alignment E=1.6e-23 PF07687: M20_dimer" amino acids 219 to 386 (168 residues), 34.1 bits, see alignment E=3.4e-12

Best Hits

KEGG orthology group: None (inferred from 97% identity to vpe:Varpa_6003)

Predicted SEED Role

"Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (503 amino acids)

>GFF3260 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases (Variovorax sp. SCN45)
MNAPLHREMPAGTLDAERALSDVTARWDGDIVRQLTDYIAIPSKSPGFDKDWAANGYLET
VLRNAAAWVEAQKVEGLKLEIVRLEGRTPVLFFEVPASGTDMDETVLMYGHLDKQPEFTG
WRNDLGPWTPKYENGLLYGRGGADDGYAVYASVAALQALKAQGVAHPRIVGLIETCEESG
SYDLLPYVDALRPRLGNVELVICLDSGAGNYDQLWLTTSLRGMASGTLKVEVLTEGIHSG
DASGLVPSSFRIMRQVLDRLEDSATGRLLPASFHCEVPADRLAQAKATAAILGEEVYKRF
PWAHYDCGGSTMFALPTTTDPVEALLNRTWKPTLSVTGAEGFPALKDAGNVLRPYTAFKL
SLRLPPLVDAAETVQTLKALLEDNAPYQARVTFESNGGATGWNAPTITPWFEDALNKASR
AHFGASCGYIGQGGTIPLMNMLSAGFPKAQMMVCGVLGPKSNAHGPNEFLHVPYAKKLTA
AVAEVIAALPAAHRAAASEPVAA