Protein Info for GFF3222 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Probable transmembrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 63 to 86 (24 residues), see Phobius details amino acids 98 to 120 (23 residues), see Phobius details amino acids 126 to 146 (21 residues), see Phobius details amino acids 197 to 213 (17 residues), see Phobius details amino acids 217 to 238 (22 residues), see Phobius details PF06912: DUF1275" amino acids 20 to 233 (214 residues), 146.5 bits, see alignment E=4.3e-47

Best Hits

KEGG orthology group: None (inferred from 78% identity to vap:Vapar_1206)

Predicted SEED Role

"Probable transmembrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (254 amino acids)

>GFF3222 Probable transmembrane protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MRRLKLLTHRRRLVASNRALGLLLAFNAGAVNAGGFLVLHMYTSHMTGFTSQLADGLVLG
NATLWLNALGAILAFVLGAAVCAMLVNWGRQHRLHSVYALPLMLEAALMFPFGLMGAITL
TWPTPFAVPITVLLLAFIMGLQNAVASKASGGSIRTTHMTGNITDVGIELGKMLYWNRRR
SDAQTQVRHNPARLQQAGGLVGMFVLGGIAGAVGFKYVGFICVVPLAALLLALSLPPLYR
DGPQLLALVRRRPA