Protein Info for GFF3205 in Xanthobacter sp. DMC5

Annotation: Fructose import ATP-binding protein FrcA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 PF00005: ABC_tran" amino acids 23 to 177 (155 residues), 112.5 bits, see alignment E=3.7e-36 PF12399: BCA_ABC_TP_C" amino acids 226 to 248 (23 residues), 32 bits, see alignment (E = 1.1e-11)

Best Hits

Swiss-Prot: 37% identical to LIVG_ARCFU: Probable branched-chain amino acid transport ATP-binding protein LivG (livG) from Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

KEGG orthology group: K01995, branched-chain amino acid transport system ATP-binding protein (inferred from 56% identity to rsq:Rsph17025_3271)

Predicted SEED Role

"Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (252 amino acids)

>GFF3205 Fructose import ATP-binding protein FrcA (Xanthobacter sp. DMC5)
MGKTLLQTTGVTRRFGGLNAVDVVDFELAAGELVAVIGPNGAGKTTFVNLLSGALRPDAG
SVMFEGRDISRLPMDARARLGIARSFQIASIFPELSVVENVALAAQAHAGHSFHFWREVA
EEAPLRRKAQAQLAGLGLSECADRPASQLSHGEKRLLEIAMALVVEPRVLLLDEPMAGLG
IAEARRMIDFIAGLKGRFSILLVEHDMEAVFSLADRVFVLASGARVADGPPEVVRADPRV
QLAYLGGEGEDL