Protein Info for GFF3197 in Xanthobacter sp. DMC5

Annotation: Vitamin B12 import ATP-binding protein BtuD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 602 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 38 to 59 (22 residues), see Phobius details amino acids 64 to 83 (20 residues), see Phobius details amino acids 89 to 106 (18 residues), see Phobius details amino acids 112 to 131 (20 residues), see Phobius details amino acids 159 to 179 (21 residues), see Phobius details amino acids 210 to 233 (24 residues), see Phobius details amino acids 247 to 272 (26 residues), see Phobius details amino acids 285 to 308 (24 residues), see Phobius details PF02653: BPD_transp_2" amino acids 34 to 295 (262 residues), 130.9 bits, see alignment E=7.7e-42 PF00005: ABC_tran" amino acids 360 to 518 (159 residues), 98.8 bits, see alignment E=6.5e-32 PF12399: BCA_ABC_TP_C" amino acids 567 to 590 (24 residues), 37.2 bits, see alignment (E = 2.6e-13)

Best Hits

KEGG orthology group: K01995, branched-chain amino acid transport system ATP-binding protein K01998, branched-chain amino acid transport system permease protein (inferred from 97% identity to xau:Xaut_4062)

Predicted SEED Role

"Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (602 amino acids)

>GFF3197 Vitamin B12 import ATP-binding protein BtuD (Xanthobacter sp. DMC5)
MRHLTRHLTLLGFAALAAILVIVPLTSGNEYELRLFMLFLIYGIIAVGLNVLVGLTGLVS
LGQAGLFALGSYTGAIVATRLGFDMISSSLIAALVAAGFGVLLAYPTVRVRGVYLAVVTI
AFGLIVENVAIEWQSLTGGTTGITSIPAPNAFGVRLSGYAFYTVLAVVLFLATAAAHNLK
VSRYGRAMLAVSQSEIAARALGVDATAMRTLAFVAAAVTAGLAGTFYAFLNSYISPDIFT
FSDSVRFLLMVILGGAASTFGPVLGAYILTYLPEYLQDFAVWQKFAYGALLLVVMFVMPR
GIMGSLAAGLKRLVPVPRAVAASEGLPAEDTLRLDPRTQKSELVARDLTVRFGGLTALAK
ASLRVKPGEVHALIGPNGAGKSTFVNTISGFYQPSEGAFELDGIQLAGKASHEIARAGLS
RTFQNTELFGEMTVLENVMVGYQQRLGYGLLAALLRTGAMRRQDDECRRAAIGLLVFVGL
QDYANEEARFLPFGLQRRLEIARALAPRPRLLLLDEPAAGLTTREIDELEEMIRRIAALG
VSVLLIEHHVELIMAVADTVTVLDYGQVIASDTPAVVQENPRVIEAYFGTSLDHANPAEV
TA