Protein Info for GFF3191 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Sodium:dicarboxylate symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 transmembrane" amino acids 18 to 36 (19 residues), see Phobius details amino acids 43 to 71 (29 residues), see Phobius details amino acids 84 to 106 (23 residues), see Phobius details amino acids 143 to 163 (21 residues), see Phobius details amino acids 184 to 206 (23 residues), see Phobius details amino acids 215 to 239 (25 residues), see Phobius details amino acids 292 to 315 (24 residues), see Phobius details amino acids 327 to 352 (26 residues), see Phobius details amino acids 363 to 379 (17 residues), see Phobius details PF00375: SDF" amino acids 18 to 397 (380 residues), 220.4 bits, see alignment E=2e-69

Best Hits

Swiss-Prot: 100% identical to SSTT_SALPB: Serine/threonine transporter SstT (sstT) from Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)

KEGG orthology group: K07862, serine/threonine transporter (inferred from 100% identity to stt:t3145)

MetaCyc: 94% identical to serine/threonine:Na+ symporter (Escherichia coli K-12 substr. MG1655)
RXN-22449; RXN0-4083

Predicted SEED Role

"Sodium:dicarboxylate symporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (414 amino acids)

>GFF3191 Sodium:dicarboxylate symporter (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPV
LVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAQDIV
PPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVGLGFALRHGNETTKNLVNDMSNA
VTFMVKLVIRFAPVGIFGLVSSTLATTGFSTLWGYAHLLVVLIGCMLLVALVVNPLLVFW
KIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINM
AGAAITITVLTLAAVHTLGVPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFG
IPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDERLANNALRS