Protein Info for GFF3181 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 190 to 211 (22 residues), see Phobius details PF02203: TarH" amino acids 2 to 172 (171 residues), 34.7 bits, see alignment E=3.4e-12 PF12729: 4HB_MCP_1" amino acids 5 to 172 (168 residues), 60 bits, see alignment E=4.7e-20 PF00672: HAMP" amino acids 210 to 260 (51 residues), 33.6 bits, see alignment 7.8e-12 PF00015: MCPsignal" amino acids 326 to 478 (153 residues), 149.3 bits, see alignment E=2e-47

Best Hits

KEGG orthology group: K05875, methyl-accepting chemotaxis protein II, aspartate sensor receptor (inferred from 99% identity to sei:SPC_3291)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (521 amino acids)

>GFF3181 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MFLHNIKIRSKLFMAFGLFIVLMVVSSALSLFSLDRANTGMQNIITNDYPTTVKANLLID
NFNDFIIAQQLMLLDEEGRWSQSSQKELDEISQRITALLDELSSNRHDAASQKIITEIRE
ARQQYLESRFRILQDIQSHNRQAAIQEMMTRTVQVQKVYKDKVQELIAVQDAQMHNAGVQ
VEGDFKTNRTLLITLALISIAAGCVMGWYIVRSITRPLDEAVRFAEAIADGDLTRHITTD
YKDETGVLLQALMAMKTRLLDIVQEVQNGSESISTAAAQIVAGNQDLAARTEEQASSVEE
TAASMEQITATVKNTADHTSEATKLSAGAASVVKNNGEMMNQVTQKMRVINDTANRMSDI
INIIDSIAFQTNILALNAAVEAARAGEHGRGFAVVAGEVRQLAQKSASSASEIRNLIEDS
TSQTQEGMHLVEKASALINGMVDNVEEMDVILREIGQASREQTDGISQINSAIGLIDAAT
QQNSCLVEESVAAAASLNEQALHLKELVNVFRVREEDTQPA