Protein Info for GFF318 in Variovorax sp. SCN45

Annotation: Uncharacterized protein YjgR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 505 PF05872: HerA_C" amino acids 7 to 505 (499 residues), 749.1 bits, see alignment E=2.3e-229 PF01935: DUF87" amino acids 20 to 194 (175 residues), 25.9 bits, see alignment E=1e-09

Best Hits

Swiss-Prot: 68% identical to YJGR_ECOLI: Uncharacterized protein YjgR (yjgR) from Escherichia coli (strain K12)

KEGG orthology group: K06915, (no description) (inferred from 92% identity to vpe:Varpa_3240)

Predicted SEED Role

"ATPase component BioM of energizing module of biotin ECF transporter" in subsystem Biotin biosynthesis or ECF class transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (505 amino acids)

>GFF318 Uncharacterized protein YjgR (Variovorax sp. SCN45)
MTEPLLIARHETVECALLPALANRHGLITGATGTGKTVTLQTMAEKLSGIGVPVFMADVK
GDLTGISQKGSIGAKLAATLKERGIDVPEPSACPVTLWDVFGDQGHPVRATISDMGPLLL
SRMLDLNDTQAGVLNLVFKIADDNGLLLLDLKDLRAMLQYVGENASQFTTQYGNISAASV
GAIQRGLVQIETQGGDKFFGEPMLNIADFMQTVGGKGVINILAADKLMNSPRLYATFLLW
MLSELFEQLPEIGDPEQPKLAFFFDEAHLLFNEAPKALVERIELVVRLVRSKGVGVYFVT
QNPLDIPDTVLAQLGNRVQHALRAFTPRDQKAVKAAASTMRQKPGLDIETAITELAVGEA
LVSFLDEKGRPSVTERVFVLPPGSQLGPITPDQRKALIANSLVAGVYEKAVDRESAYEKL
KGRADSAPGAPTATLPGGKPAAEASGSGMGGMLNDMLFGTTGPRGAKHDGLVQTMAKSAV
RTMGTSVGKEILRGVLGGIFGSKKR