Protein Info for GFF318 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Putative transport protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 397 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 56 to 78 (23 residues), see Phobius details amino acids 86 to 105 (20 residues), see Phobius details amino acids 111 to 133 (23 residues), see Phobius details amino acids 146 to 170 (25 residues), see Phobius details amino acids 177 to 196 (20 residues), see Phobius details amino acids 217 to 239 (23 residues), see Phobius details amino acids 254 to 275 (22 residues), see Phobius details amino acids 282 to 301 (20 residues), see Phobius details amino acids 307 to 330 (24 residues), see Phobius details amino acids 342 to 363 (22 residues), see Phobius details amino acids 369 to 389 (21 residues), see Phobius details PF07690: MFS_1" amino acids 26 to 335 (310 residues), 126.1 bits, see alignment E=7.9e-41

Best Hits

Swiss-Prot: 100% identical to NEPI_SALCH: Purine ribonucleoside efflux pump NepI (nepI) from Salmonella choleraesuis (strain SC-B67)

KEGG orthology group: K03445, MFS transporter, DHA1 family, purine ribonucleoside efflux pump (inferred from 99% identity to set:SEN3598)

MetaCyc: 87% identical to purine ribonucleoside exporter (Escherichia coli K-12 substr. MG1655)
RXN0-18; RXN0-22

Predicted SEED Role

"Putative transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (397 amino acids)

>GFF318 Putative transport protein (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MNENIAEKFRADGVARPNWSAVFAVAFCVACLITVEFLPVSLLTPMAQDLGISEGVAGQS
VTVTAFVAMFSSLFITQIIQATDRRYIVILFAVLLTASCLMVSFANSFTLLLLGRACLGL
ALGGFWAMSASLTMRLVPARTVPKALSVIFGAVSIALVIAAPLGSFLGGIIGWRNVFNAA
AVMGVLCVIWVVKSLPSLPGEPSHQKQNMFSLLQRPGVMAGMIAIFMSFAGQFAFFTYIR
PVYMNLAGFDVDGLTLVLLSFGIASFVGTSFSSYVLKRSVKLALAGAPLLLALSALTLIV
WGSDKTVAAAIAIIWGLAFALVPVGWSTWITRSLADQAEKAGSIQVAVIQLANTCGAAVG
GYALDNFGLLSPLALSGGLMLLTALVVAAKVRITPMS