Protein Info for GFF3176 in Variovorax sp. SCN45

Annotation: Two-component transcriptional response regulator, LuxR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 157 PF00196: GerE" amino acids 95 to 150 (56 residues), 59.1 bits, see alignment E=1.2e-20

Best Hits

KEGG orthology group: None (inferred from 80% identity to vap:Vapar_3838)

Predicted SEED Role

"Two-component response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (157 amino acids)

>GFF3176 Two-component transcriptional response regulator, LuxR family (Variovorax sp. SCN45)
MTHLTRNDCAIALRLLEQLESWGSPVRHHGSRDGSGSRAVRRIAAKAPGWREFRRAELQA
DYYRRVGLEHAVAVAFLYRLACRADAPLPDAPPAALTPREGDVMHWLSRGKTDAEIAALL
EISPRTVHKHLEHVYVKLGVETRTAAVMRALAMGGAP