Protein Info for PS417_16165 in Pseudomonas simiae WCS417

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF13379: NMT1_2" amino acids 23 to 192 (170 residues), 32.1 bits, see alignment E=2.7e-11 PF04069: OpuAC" amino acids 27 to 231 (205 residues), 32.7 bits, see alignment E=1.5e-11 TIGR01728: ABC transporter, substrate-binding protein, aliphatic sulfonates family" amino acids 28 to 309 (282 residues), 210.9 bits, see alignment E=1.2e-66 PF09084: NMT1" amino acids 56 to 249 (194 residues), 56.1 bits, see alignment E=1.3e-18 PF12974: Phosphonate-bd" amino acids 71 to 192 (122 residues), 35.3 bits, see alignment E=2e-12 PF16868: NMT1_3" amino acids 111 to 186 (76 residues), 29.5 bits, see alignment E=1.5e-10

Best Hits

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 96% identity to pfs:PFLU3722)

Predicted SEED Role

"ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components" in subsystem Alkanesulfonate assimilation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TYG2 at UniProt or InterPro

Protein Sequence (314 amino acids)

>PS417_16165 ABC transporter substrate-binding protein (Pseudomonas simiae WCS417)
MSIRRPLAAVAGLLAFSVAVSAEAQETVRIGYQKSSTLITLLKTQGTLEKALKADNIDVS
WHEFPSGLPLLEALNVGNVDISADVADTVPIFAQAAQAKLTYFAQEAPSPSAQAIVVRKD
SPIQQLADLKGKKIAVTKAAGTHYLLIAALAQTGLEFSDITPAYLSPADGRAAFENNKVD
AWVTWEPFLTSVQRQLPTRTLADGAGLASYKRYYLTGTPYAKAHPDVLKVVYAQLEKTGQ
WVKTHPQDAAKVLGPLWGNLDVATVEAANAHRSYQVQPVTIDQLGEQQKIADAFFKAGLL
PKAVDAKDVQTWKP