Protein Info for GFF3157 in Variovorax sp. SCN45

Annotation: Sulfite dehydrogenase (quinone), membrane-anchor subunit SoeC (EC 1.8.5.6)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 38 to 61 (24 residues), see Phobius details amino acids 83 to 102 (20 residues), see Phobius details amino acids 110 to 134 (25 residues), see Phobius details amino acids 146 to 167 (22 residues), see Phobius details amino acids 173 to 194 (22 residues), see Phobius details amino acids 250 to 269 (20 residues), see Phobius details amino acids 275 to 294 (20 residues), see Phobius details PF04976: DmsC" amino acids 3 to 204 (202 residues), 59.7 bits, see alignment E=1.6e-20

Best Hits

KEGG orthology group: K07308, anaerobic dimethyl sulfoxide reductase subunit C (DMSO reductase anchor subunit) (inferred from 88% identity to vpe:Varpa_4398)

Predicted SEED Role

"Anaerobic dimethyl sulfoxide reductase chain C (EC 1.8.5.3)" (EC 1.8.5.3)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.8.5.3

Use Curated BLAST to search for 1.8.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (310 amino acids)

>GFF3157 Sulfite dehydrogenase (quinone), membrane-anchor subunit SoeC (EC 1.8.5.6) (Variovorax sp. SCN45)
MHPAFSILFFTTLAGAAQGLVFALALAVLFGLDLAPGFLGIALGVAEVLLVAGLAASFMH
LGRKTRAWRAVLMWRTSWMSREVIVLPVFIALVALWWLSLRLGIGAPWSWLLPLLVLYGA
MLLWYCTAMIYACLRFIEEWAHPLTIVNFTLIGLSSGLVLACAMAAASGEARFVQVFGPW
ALVATLAAWAARGGALRRNARLRHKSTLQSATGIRTQKLVQKSMGMSAGSFNTREFFHGV
SLAALGNMKIGFLLLAFALPALMVLWGIFSASAWPWLLAVLVQAPGLLAERWFFFAQARH
PQNLYYQVVS