Protein Info for PS417_16140 in Pseudomonas simiae WCS417

Annotation: ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details PF00005: ABC_tran" amino acids 35 to 173 (139 residues), 120.2 bits, see alignment E=5.1e-39

Best Hits

Swiss-Prot: 45% identical to Y412_METJA: Uncharacterized ABC transporter ATP-binding protein MJ0412 (MJ0412) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K02049, sulfonate/nitrate/taurine transport system ATP-binding protein (inferred from 96% identity to pfs:PFLU3717)

MetaCyc: 45% identical to taurine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-64-RXN [EC: 7.6.2.7]

Predicted SEED Role

"Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB" in subsystem Alkanesulfonate assimilation or Alkanesulfonates Utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U0G2 at UniProt or InterPro

Protein Sequence (262 amino acids)

>PS417_16140 ABC transporter (Pseudomonas simiae WCS417)
MVALAHAVSASESLALRIENLSHGFALDGQHLPVLERVSLDVAPGEFVALLGPSGCGKST
LLRLVAGLEPADSGRLLADGEAITGPDPSRVVVFQDPTLYPWRRVWDNVAVGLEAQGLLK
THAAKVDEALEKVGLSQFARAYPRQLSGGMAQRVALARALVNQPRLLILDEPLGKLDSLT
RITLQKELIDLWQRQGYTALLVTHDVEEALLLANRVIVFSDRPARIQAQLTIDRAYPRHR
DDPYLVDLRRQILGLLGLGENW