Protein Info for GFF3142 in Variovorax sp. SCN45

Annotation: Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1203 PF01558: POR" amino acids 752 to 938 (187 residues), 67 bits, see alignment E=2.4e-22 PF20169: DUF6537" amino acids 970 to 1170 (201 residues), 196.2 bits, see alignment E=6.1e-62

Best Hits

Predicted SEED Role

"Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits" in subsystem Aromatic amino acid interconversions with aryl acids

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1203 amino acids)

>GFF3142 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits (Variovorax sp. SCN45)
MNAPHNATALRRPGYQLSDNLWAPSGSVFITGTQALIRVLVMQGWRDAARGLHTQGFVSG
YRGSPLGMVDQAIWKAGERFKETGIRFVPAVNEELAATQVLGTQRVESDPERTVDGVFAM
WYGKGPGVDRAGDALKHGNAYGSSPHGGVLVVAGDDHGCVSSSMPHQSDHAFMAWRMPVM
QPSCVAEYLEFGLYGYELSRYSGAWVGMAALSEVVESAGTVDLDVVNARVQAWEDADTVR
AATGHQAPADGLHYRWPDLPSLRIESRLEDKLAAVAAFTRRNSIDRDVIVSEHAKVGIVT
CGKAHHDLMEVLRRLELSPEQLARAGVRLYKIGLSFPVEQTRIKAFAKGLEEILIVEEKG
AVVETQLRDIFYNAPADARPVLVGKHDRAGQPLVSALGELRPSRLIELVAHWLAVHFPDN
RDLGDHLQHVRDFTPPELLGNASDAVKRLPYFCAGCPHNTSTKVPEGSTARAGIGCHFMA
NWMDRSTAGLIQMGGEGVDWISHAMFTKTPHVFQNLGDGTYYHSGYLAIRQAVAAKATLT
YKILFNDAVAMTGGQPVDGVISVDAIARQVESEGVSKVVVVSDAIGKYDDIKGRFPQGTE
FHDRAALDDVQRRLREMQGVTVLIYEQTCAAEKRRRRKKGEMADPPKRLFINEAVCEGCG
DCTVQSNCVAVLPHETPMGRKRKIDQTSCNKDYSCAKGFCPSFVGVTGGKLRRKSGALAA
GRDAFLHRVAALQHPAAHAWNAPYDLLVTGVGGTGVVTVGAVIAMAAHLEGKAASVLDFM
GFAQKGGSVLSFVRLADSRERLHQVRIDTQQADAILACDVVVGASADALQTVRHGRTRVL
ANIHEIPVAESLRNPDADLHVDLLLEKMRFVAGEEQVETFDAQSLAEEFLGDTLAANIVA
TGYAWQRGLVPLSLEALMHAIELNGVAVAANQSAFSLGRLAAGDPAALDQLRAAPAADAQ
SSQADERPLDMLIADARRHLTGYQNAAWADRFEKRIRGLQAREAALQGGDSSLPFTRNAA
RSLLKLMSYKDEYEVARLYTDGAFLKKLSEQFEGELKLEFHMAPPVVARGSHGRAPAKIR
VGSWMLPAMRWLAHGKRLRGTAFDPFGRTGERRAERELISHFDGLFDAMAGELSADNQSL
AARIAALPMSIRGFGHVKLANLEAAQVREAELLHRFAPSRYPKPASAPGAGQIRGIAIVA
GAR