Protein Info for PS417_15980 in Pseudomonas simiae WCS417

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 352 transmembrane" amino acids 20 to 37 (18 residues), see Phobius details amino acids 43 to 62 (20 residues), see Phobius details amino acids 76 to 95 (20 residues), see Phobius details amino acids 116 to 141 (26 residues), see Phobius details amino acids 147 to 167 (21 residues), see Phobius details PF05230: MASE2" amino acids 14 to 101 (88 residues), 102.6 bits, see alignment E=9.8e-34 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 183 to 343 (161 residues), 169.7 bits, see alignment E=2.3e-54 PF00990: GGDEF" amino acids 186 to 340 (155 residues), 150.1 bits, see alignment E=4.8e-48

Best Hits

KEGG orthology group: None (inferred from 92% identity to pfs:PFLU3650)

Predicted SEED Role

"Two-component response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UAY7 at UniProt or InterPro

Protein Sequence (352 amino acids)

>PS417_15980 histidine kinase (Pseudomonas simiae WCS417)
MSAAEGTGLPLASRLYRSRTLGLTLGFVCVVFGMYPLDPAWWVWAWMLINAFVWPHVAFQ
LTRRSASALRSERRNLLFDSFCGGFWVGAMHFNPLPSVTTLSMMSMNNVAIGGPRFMLAG
WVAQALGLGTALLIFTPAFIAVTTQAQLYACLPILMLYPLALGWICYRQALTLARHKREL
LALSRTDSLSGLLNHGAWKDHLEIEFQRCRRDSMGAVIALIDIDHFKTINDTYGHVTGDI
VLRQLSKVLRQNLRATDLAGRYGGDEFCVILPGMPLNRATEVMDALRDRFNALAYAQDPT
LRVSLSIGLAPYQPTHADSTSWLNDADQALYDAKSSGRNRVSTVQEGWLRSV