Protein Info for PS417_15775 in Pseudomonas simiae WCS417

Annotation: short-chain dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 63 to 80 (18 residues), see Phobius details amino acids 90 to 110 (21 residues), see Phobius details amino acids 116 to 137 (22 residues), see Phobius details amino acids 144 to 163 (20 residues), see Phobius details amino acids 174 to 194 (21 residues), see Phobius details amino acids 210 to 230 (21 residues), see Phobius details amino acids 236 to 254 (19 residues), see Phobius details amino acids 266 to 289 (24 residues), see Phobius details amino acids 297 to 320 (24 residues), see Phobius details amino acids 332 to 351 (20 residues), see Phobius details amino acids 357 to 375 (19 residues), see Phobius details PF05940: NnrS" amino acids 14 to 385 (372 residues), 348 bits, see alignment E=4.2e-108

Best Hits

KEGG orthology group: K07234, uncharacterized protein involved in response to NO (inferred from 75% identity to pba:PSEBR_a3163)

Predicted SEED Role

"NnrS protein involved in response to NO" in subsystem Denitrification or Nitrosative stress or Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U0B4 at UniProt or InterPro

Protein Sequence (391 amino acids)

>PS417_15775 short-chain dehydrogenase (Pseudomonas simiae WCS417)
MHVLDRRKAMSITPLLRLAFRPFFLGACLLAALVVPLWLLALGGLTGEWQPAGGWLAWHR
HELLFGFGLAIIAGFLLTAVQTWTGRAGLSGTPLAVLAALWLAARVGWLLNVPMPLLAVL
ELSFPLAVAGVMGWTLWKVRQTRNYPIVLVLVLLALADGLSLSDPALQRQSVLTGLWLVA
AMMGLIGGRVIPFFTQRGLGRAEAVKPWPWLDHLLLSGSILVALLYANGWALMPNLWVGV
LFAALGLGHLLRWLRWQDRGLWRVPLLWSLHLAYAWLALACLGMALWHFGAAFNPSLAVH
ALTIGAMAGLILAMITRVSLGHTGRPLQPPPGMTLAFALLNLACVCRVWLVLVWPLAALW
LAGLCWSIGMGLYLWRYGPMLWQARVDGHPG