Protein Info for GFF2989 in Xanthobacter sp. DMC5

Annotation: Vitamin B12 import ATP-binding protein BtuD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 663 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 31 to 52 (22 residues), see Phobius details amino acids 63 to 82 (20 residues), see Phobius details amino acids 88 to 106 (19 residues), see Phobius details amino acids 113 to 129 (17 residues), see Phobius details amino acids 174 to 194 (21 residues), see Phobius details amino acids 223 to 242 (20 residues), see Phobius details amino acids 248 to 266 (19 residues), see Phobius details amino acids 273 to 289 (17 residues), see Phobius details amino acids 295 to 315 (21 residues), see Phobius details amino acids 322 to 341 (20 residues), see Phobius details amino acids 347 to 364 (18 residues), see Phobius details PF02653: BPD_transp_2" amino acids 31 to 293 (263 residues), 141.6 bits, see alignment E=5.7e-45 PF00005: ABC_tran" amino acids 425 to 585 (161 residues), 104.9 bits, see alignment E=1.1e-33 PF12399: BCA_ABC_TP_C" amino acids 634 to 659 (26 residues), 49.5 bits, see alignment (E = 5e-17)

Best Hits

KEGG orthology group: K01995, branched-chain amino acid transport system ATP-binding protein K01998, branched-chain amino acid transport system permease protein (inferred from 88% identity to xau:Xaut_4055)

Predicted SEED Role

"Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (663 amino acids)

>GFF2989 Vitamin B12 import ATP-binding protein BtuD (Xanthobacter sp. DMC5)
MLARRLLSSTGSLIGLAVLVVLPFVVTSPYYLHLLVTIAIFSILLLGLDVVFGYTGEVSI
GHAALFGIGAYTAGCLAMHFGIGFWPALPLAIIVASVFGVVLALPALRVTGPYLAMVTLA
FGTIVQILINEMTDLTNGPLGIKLTTPLFIDLRWLGDTIPLFDMSLKRMKEVEYYYIAAI
ALVLTLIIINRILASHLGRAFEALRDSPIASDCMGVSVYKHKVLAFVVSAGLAGLAGALF
AYSEQYIAPNNFGFELSVQFLLAVTVGGRKSRLGPILGAVIIVFLPNLLSDIELFRYIAG
GIALVAVIAGARAFVKDPENRVRNAIPVVLCLAFFVFSLLLQKITDYKLAVFGVMILFVV
YYLPDGIVGFLKRAVAQLWPSLVQTHAVIHADTHGKAVTASHEGHSGVLLHVDNVVMQFG
GLRALDQVSIEVKPGTIHGLIGPNGSGKSTMMNVLTGIYVPTAGAVRFKGQEMAGKTSSD
IAGDGIARTFQNVQLFAELTLIENVLVGLHHTYQATFAEVALGLPRIRREEKAARERAMS
LLHFVGLADLANEEARNLPYGKQRLLEIARALALDPALLLLDEPAAGLTAPDIKHLVEII
RKVRHAGLTIVLIEHHMDVVMGLCDTVTVLDFGQKIAEGKPAEVQANERVIEAYLGGAAA
AAE