Protein Info for GFF2975 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: putative 2-pyrone-4,6-dicarboxylic acid hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 277 PF04909: Amidohydro_2" amino acids 13 to 271 (259 residues), 149.4 bits, see alignment E=9.5e-48

Best Hits

KEGG orthology group: K07046, (no description) (inferred from 51% identity to bpe:BP1159)

Predicted SEED Role

"putative 2-pyrone-4,6-dicarboxylic acid hydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (277 amino acids)

>GFF2975 putative 2-pyrone-4,6-dicarboxylic acid hydrolase (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSSATARWPAGSCDCHFHVFDAARYPYAEGRHYTPPDAPLAAYLAMCESVGIERGVLVHP
TVFGADHRSFEDILAAHPQRLRGVAVVSPDTPEADIARWHALGARGTRVTTIFQGPDLAR
IREIAARVKPFGWHVQILVDVVRHPGLVAQVRALGVPVVVDHMGHHGAAALLASPGFANL
CSQLLAGEVWAKLSAPYRLSADSGRDPLVGEVAQALLRANASRLVWGSDWPHPTSPHPVP
SDERLAALALEWLPDEATRQAVLVRNPQRLYWGGGAD