Protein Info for GFF2969 in Xanthobacter sp. DMC5

Annotation: High-affinity branched-chain amino acid transport system permease protein LivH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 44 to 63 (20 residues), see Phobius details amino acids 69 to 93 (25 residues), see Phobius details amino acids 103 to 124 (22 residues), see Phobius details amino acids 146 to 171 (26 residues), see Phobius details amino acids 201 to 222 (22 residues), see Phobius details amino acids 228 to 248 (21 residues), see Phobius details amino acids 254 to 274 (21 residues), see Phobius details amino acids 280 to 299 (20 residues), see Phobius details PF02653: BPD_transp_2" amino acids 10 to 289 (280 residues), 156.3 bits, see alignment E=4.4e-50

Best Hits

Swiss-Prot: 32% identical to BRAD_PSEAE: High-affinity branched-chain amino acid transport system permease protein BraD (braD) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 56% identity to pol:Bpro_3335)

Predicted SEED Role

"High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (306 amino acids)

>GFF2969 High-affinity branched-chain amino acid transport system permease protein LivH (Xanthobacter sp. DMC5)
MDPGLLAQYLFNGLMLGTIYAIVAVGFSLFFGVLDVIKFSHGDVVTVGAFSAFGAAGLMA
ALVTLSGPLALAVGLIAALGAGALSGVIIGRLLVLPLKNAPGVNVLLATLMAGTVLREAI
RLGVPNGGNPKPFPALLPDGVLKAGSFSVGVDSVIILLAGLAVVLATHLVITRTRLGLSI
RAVAQDEEVAQLAGVSFNRTVLGTFALGSMLAGLAGLMLGLYYREINFNMGVMLGIIGFA
CAVVGGLGSLIGPIIGGFLFAGVQTLVTVVLPFTSAYKDVVAFAVIIALIGLFPTGLIAE
KSSERV