Protein Info for GFF2960 in Variovorax sp. SCN45

Annotation: Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 187 PF13302: Acetyltransf_3" amino acids 26 to 165 (140 residues), 41.2 bits, see alignment E=4.1e-14 PF00583: Acetyltransf_1" amino acids 64 to 164 (101 residues), 37 bits, see alignment E=5.4e-13 PF13508: Acetyltransf_7" amino acids 84 to 165 (82 residues), 27.4 bits, see alignment E=5.4e-10

Best Hits

KEGG orthology group: None (inferred from 85% identity to vpe:Varpa_1859)

Predicted SEED Role

"Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (187 amino acids)

>GFF2960 Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative (Variovorax sp. SCN45)
MATQAPHGYPGHLAEDWQLADGTPVRIRPIRAEDLAMHSAFVAGLSNETGYRRLLSPRKP
QPDELWRMTHIDYDRELALIATTVIEGAEQQMGVVRYVRGDTPGTAQVAEFAVVIADAWQ
HRGVAHKLMRKLIEAAAGAGVRQLSDITLYDNTGMLALARKLGFRLQRDAANPNVTRLRL
ALPTPAT