Protein Info for GFF2939 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: ATP synthase F0 sector subunit a

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 transmembrane" amino acids 33 to 56 (24 residues), see Phobius details amino acids 95 to 114 (20 residues), see Phobius details amino acids 145 to 165 (21 residues), see Phobius details amino acids 188 to 208 (21 residues), see Phobius details amino acids 226 to 250 (25 residues), see Phobius details amino acids 259 to 282 (24 residues), see Phobius details TIGR01131: ATP synthase F0, A subunit" amino acids 31 to 283 (253 residues), 132 bits, see alignment E=1.6e-42 PF00119: ATP-synt_A" amino acids 40 to 281 (242 residues), 182.9 bits, see alignment E=4e-58

Best Hits

Swiss-Prot: 72% identical to ATP6_ACIAC: ATP synthase subunit a (atpB) from Acidovorax citrulli (strain AAC00-1)

KEGG orthology group: K02108, F-type H+-transporting ATPase subunit a [EC: 3.6.3.14] (inferred from 72% identity to aav:Aave_0366)

Predicted SEED Role

"ATP synthase F0 sector subunit a"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (288 amino acids)

>GFF2939 ATP synthase F0 sector subunit a (Hydrogenophaga sp. GW460-11-11-14-LB1)
MAAEGTLTPGEYIRHHLVHLTNHKQGSIVDFSVINIDSVVVSALLGLLTVFVLWRAARVA
TAGVPGRFQAAVEMLVEMVDSQAKSVIHNAQSRKLVAPLALTVFVWIFMMNFMDMIPVDL
IPQIWHSAGPAMGFKDYLRVVPTADLSTTLGLSVSVLLMCLFYNIKIKGLGGWAHELVSA
PFGTSKNPLWAVLLGIVNFLMQMIEFVAKTVSHGMRLFGNMFAGELVFMLIALLGAYATL
SLGGGLFFIGHLIAGTVWTLFHILVITLQAFIFMMLALIYLGQAHDAH