Protein Info for GFF2937 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: D-alanine aminotransferase (EC 2.6.1.21)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 PF01063: Aminotran_4" amino acids 35 to 258 (224 residues), 143.2 bits, see alignment E=5.7e-46

Best Hits

Swiss-Prot: 40% identical to DAAA_BACLI: D-alanine aminotransferase (dat) from Bacillus licheniformis

KEGG orthology group: K00824, D-alanine transaminase [EC: 2.6.1.21] (inferred from 67% identity to pol:Bpro_0317)

Predicted SEED Role

"D-alanine aminotransferase (EC 2.6.1.21)" in subsystem Pyruvate Alanine Serine Interconversions (EC 2.6.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (294 amino acids)

>GFF2937 D-alanine aminotransferase (EC 2.6.1.21) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTDLPDSLCFLDGAYGPLRDARVSVLDRGFIFGDGVYEVLPAYGGRVFRFAEHMARLARS
LRELRMPNPFSSDEWLGIARRLIADQQARGVNDQLIYLQITRGVAPRDHVMPPGLKPTVF
VMANPMKLATPEQRDHGVACVTADDFRWRKAHIKATSLLGSVLARQIAADAGAVEVVMFR
DGFLSEGASSNVWVVKDGVVMGPPKDNLVLEGIRFGLVEELCRQQDLRYELRRVTRAEVL
SADELLLSSATKEVLPITVLDGAPVGHGAQRGRPGPAYARLYAGYQRAVAAQSI