Protein Info for GFF2930 in Variovorax sp. SCN45

Annotation: Chaperone protein DnaJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 379 PF00226: DnaJ" amino acids 6 to 70 (65 residues), 96.4 bits, see alignment E=1.2e-31 TIGR02349: chaperone protein DnaJ" amino acids 6 to 354 (349 residues), 443.5 bits, see alignment E=3.3e-137 PF01556: DnaJ_C" amino acids 126 to 338 (213 residues), 177.2 bits, see alignment E=3.5e-56 PF00684: DnaJ_CXXCXGXG" amino acids 152 to 212 (61 residues), 66 bits, see alignment E=4.4e-22

Best Hits

Swiss-Prot: 80% identical to DNAJ_POLSJ: Chaperone protein DnaJ (dnaJ) from Polaromonas sp. (strain JS666 / ATCC BAA-500)

KEGG orthology group: K03686, molecular chaperone DnaJ (inferred from 91% identity to vap:Vapar_1711)

MetaCyc: 60% identical to chaperone protein DnaJ (Escherichia coli K-12 substr. MG1655)
1.8.4.-

Predicted SEED Role

"Chaperone protein DnaJ" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (379 amino acids)

>GFF2930 Chaperone protein DnaJ (Variovorax sp. SCN45)
MATKRDYYETLGVPKNASEEEIKKAYRKLAMKHHPDRNHGDTAKDAEAKFKEVKEAYEML
SDGQKRAAYDQYGHAGVDPNMRGGPGAEGFGGFAEAFGDIFGDVFGGGGRGRTSSGRQVF
RGSDLSYAMEITLEEAAEGKTTEIRIPTWDECDTCHGSGAKPGTKPITCTTCHGAGAVQM
RQGFFSVQQTCPTCHGSGKIIPEPCTACHGQGKIKRNKTLEVKIRAGIDDGQRMRVTGSG
EPGVNGGPPGDLYIEIRLKKHDIFERDGDNLHCVVPVSMTTAALGGEINVPTLKGAAAID
IPEGTQSGKQFRLRGKGIKGVNSSYPGDLYCHVRVETPVKLTEFQRKLLKDLDDSLKKGG
EKHSPTDKGWFDKAKEFFS