Protein Info for PS417_14960 in Pseudomonas simiae WCS417

Annotation: ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 transmembrane" amino acids 7 to 27 (21 residues), see Phobius details amino acids 131 to 151 (21 residues), see Phobius details PF00672: HAMP" amino acids 152 to 200 (49 residues), 32.5 bits, see alignment 1.3e-11 PF00512: HisKA" amino acids 206 to 270 (65 residues), 38.6 bits, see alignment E=1.4e-13 PF02518: HATPase_c" amino acids 317 to 421 (105 residues), 81.1 bits, see alignment E=1.3e-26

Best Hits

KEGG orthology group: K02484, two-component system, OmpR family, sensor kinase [EC: 2.7.13.3] (inferred from 95% identity to pfs:PFLU3483)

Predicted SEED Role

"Sensory histidine kinase in two-component regulatory system with RstA" in subsystem Orphan regulatory proteins

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U7D3 at UniProt or InterPro

Protein Sequence (426 amino acids)

>PS417_14960 ATPase (Pseudomonas simiae WCS417)
MLRLYIRLYIILALGLAGAIWLVNYTFDELLPEANETYNREAMRGPAYALVEQLRPLLGD
ARQARLGELQPHYGLHLKLVQRDDLALNPREQQLLAAGQLVVRGDFMEFIANLDGGPQLL
NIKLPDEPKWLYLWAYSLLGLSLAIVLYFWVRPHWRDLEHIRLAAQRFGDNELSSRILLP
RRSTVRELAGHFNQMAERIESLIANQRELTNAVSHELRTPIARLSFELDQLKQQADPRQR
GELIADMYADLGELEEMVSELLTYASLERGATQVTRESIEALSWLDSVIGSVALEAEAAG
IQLSLRTCEVDFIQIEPRFMARAVINLLRNAIRYAERRVEVSLVKFGSGYEVRVCDDGPG
VPEDGRAKIFQPFMRLDASRDRRTGGFGLGLALVQRVSQWHGGQVQVLDSEWGGASFRMT
WAYVES