Protein Info for PS417_14945 in Pseudomonas simiae WCS417

Annotation: beta-lactamase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 604 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00144: Beta-lactamase" amino acids 45 to 368 (324 residues), 207.7 bits, see alignment E=1.3e-65

Best Hits

KEGG orthology group: None (inferred from 59% identity to pfl:PFL_2640)

Predicted SEED Role

"Beta-lactamase class C and other penicillin binding proteins" in subsystem Beta-lactamase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UIM8 at UniProt or InterPro

Protein Sequence (604 amino acids)

>PS417_14945 beta-lactamase (Pseudomonas simiae WCS417)
MLRTLRGLPLLGCLLGSIGCHGQSPAPPSIAKGDYSAIIRYLQTRIPRDMAQDNIPGLSI
ALVNGQELIWARGFGMADKAKGLPVTPNTAFRAGAISKLLTASAALQLVEEQRLTLDAPL
QQTLREFYVRSRFHADQQAADRDITLRRLLSHQSGLPSEHLRDLRNSYAMGQMPMRLSGV
WLSTPPGTQVAYSNLGYALVGAAIERSSGKEFEAQMQHSLLKPLEMDRASFVGTAAQVGF
RALGYQEGVASTDAQLRDIAAGGLWASPKDLSHYVQMLFAKGLYKGKRVMASRSIDEMFT
QQNTGNALDFDCQIGLAWFLAPCGDAPVGPRVRTYQHSGGGDDFAAQLSLLPDHQLAVII
MANDSNAEDLVATLATDTLRLMLEAQTGTPVCSDDCQSPRHGLKLRQVPTAIDRQRLAGF
YATAWGVFRIKDDEQRLRGELAGFNFELLRDDQGWLRAQKKLFGFWLKDLGELGHVQLDV
ITVQGRQMLTARSHGQRIPIGERIDPPPLPMAWADTVGTYQVLNSFEPDAPLSGISVRLE
EGFLVIRGQLHDEPLTDYILLPVDNAHAVLAGTGYGLGDTVSRQINGLSASGYAFKRTHP
PLSF