Protein Info for GFF290 in Variovorax sp. SCN45

Annotation: Cell division coordinator CpoB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 249 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR02795: tol-pal system protein YbgF" amino acids 128 to 245 (118 residues), 116.2 bits, see alignment E=6.5e-38 PF13525: YfiO" amino acids 132 to 249 (118 residues), 40.5 bits, see alignment E=1.3e-13 PF09976: TPR_21" amino acids 133 to 231 (99 residues), 29.2 bits, see alignment E=3.3e-10 PF13432: TPR_16" amino acids 133 to 198 (66 residues), 38.1 bits, see alignment E=7.9e-13 PF13174: TPR_6" amino acids 140 to 161 (22 residues), 18 bits, see alignment (E = 1.6e-06) amino acids 167 to 198 (32 residues), 18.9 bits, see alignment 8.3e-07 amino acids 204 to 235 (32 residues), 24.5 bits, see alignment 1.4e-08 PF07719: TPR_2" amino acids 165 to 198 (34 residues), 26.1 bits, see alignment 2.7e-09 PF13181: TPR_8" amino acids 165 to 198 (34 residues), 16.9 bits, see alignment 2.6e-06 PF14559: TPR_19" amino acids 179 to 243 (65 residues), 38.3 bits, see alignment E=6.3e-13

Best Hits

KEGG orthology group: None (inferred from 94% identity to vpe:Varpa_2719)

Predicted SEED Role

"TPR repeat containing exported protein; Putative periplasmic protein contains a protein prenylyltransferase domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (249 amino acids)

>GFF290 Cell division coordinator CpoB (Variovorax sp. SCN45)
MQRAVLRGAALAAALLCVSVGSQAALFEDDEARRAILDLRQRVEAMRQQTDQRLTDENGQ
LRRSLLDLQNQIEQMRGDLARMTGQNEQLTRTVSEMQSRQTTLDDKLKQSEPSKVSVDGR
EFNADPKEKADFDAALGVFRSGQFAQAQTAFAEFVKRYPQSGYNASALFWLGNAQYATRN
YNEAIANFRSMLSLAPDHAKAPEAVLSIANCQIELKDTRAARRTLEDLTKAYPQSEAAQA
GRERLSRLR