Protein Info for GFF29 in Xanthobacter sp. DMC5

Annotation: 2,3-diketo-L-gulonate-binding periplasmic protein YiaO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details transmembrane" amino acids 103 to 121 (19 residues), see Phobius details amino acids 187 to 200 (14 residues), see Phobius details TIGR00787: TRAP transporter solute receptor, DctP family" amino acids 41 to 295 (255 residues), 214.3 bits, see alignment E=1e-67 PF03480: DctP" amino acids 58 to 314 (257 residues), 220.5 bits, see alignment E=1.5e-69

Best Hits

KEGG orthology group: None (inferred from 72% identity to bra:BRADO1713)

Predicted SEED Role

"TRAP-type C4-dicarboxylate transport system, periplasmic component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (342 amino acids)

>GFF29 2,3-diketo-L-gulonate-binding periplasmic protein YiaO (Xanthobacter sp. DMC5)
MTTFNRRSFLQFTAACGAAVGGVSLAAPAVFAKPEPLKLKFGNDLPDSHSVNVRLREAIA
AISAETDGALDISLFPNNQLGSDPDMMSQLRSGALELATMPGTVLSTILPITALTGVGFA
FTSYDKVWAAMDGAVGDLIRSNLVKANLVGFDKVWDNGFRQITSSTRPIREPGDLAGFKI
RVPLVPLWVSMFSAFGASPVSIPLAEAYSALQTKIADGQENPLALIYTAKFFEVQKYCSL
TNHAWDGFWLLASGKVWKSVPDDLKQVMAKHFNAAAIKQRSDIVKANQTLQADLEAKGLV
FNTTNAEVFQQALAKTSFYKDARAKFGDEAWNLLQKFAGPVG