Protein Info for GFF2899 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: probable bifunctional hydroxylase/oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 786 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details PF01494: FAD_binding_3" amino acids 11 to 157 (147 residues), 23.6 bits, see alignment E=3e-09 PF00724: Oxidored_FMN" amino acids 421 to 748 (328 residues), 209.9 bits, see alignment E=6.7e-66

Best Hits

KEGG orthology group: K09461, anthraniloyl-CoA monooxygenase [EC: 1.14.13.40] (inferred from 72% identity to cti:RALTA_A1992)

Predicted SEED Role

"probable bifunctional hydroxylase/oxidoreductase"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.13.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (786 amino acids)

>GFF2899 probable bifunctional hydroxylase/oxidoreductase (Hydrogenophaga sp. GW460-11-11-14-LB1)
MKTPVPALRRILCIGGGPAGLYFALLMKRRDPSLTVTVVERNRPFDTFGWGVVLSDQTLG
NLREADPESAALIGEAFNHWDDIEVFFKGGRVRSGGHGFCGIGRKKLLNILQERCLALGV
NLVFETDVTDDQALAAQYEADLVIASDGLNSRIRTRYADTFQPDIDTRQCRFVWLGTQKT
FDAFTFAFVQTEHGWFQAHAYKFDGETSTFIVETPEEVWKAHGIDQMSQEDGVAFCEKLF
APYLDGHALISNASHLRGSAIWIRFPRVICHTWVRWQDIAGRKTPIVLMGDAAHTAHFSI
GSGTKLALEDAIDLADEFSRHANADVAEVLQGYEARRSVEVLKIQNAARNSTEWFENVDR
YTGMEVEQFAYSLLTRSQRISHENLRLRDAKWLEGYEAWLESQAKPGVPVKKHPTPPMLL
PLTVRGLTLKNRIVVSPMAQYSAVDGVVGDYHLVHLGARAMGGAALVMVEMTSPTPEGRI
TPGCPGLWNDAQQAGLKRIVDFVHGSSSAKIGLQLGHSGAKGSTQLGWEQIDEPLPSGNW
PLLSASAVPYGEHNQVPRAMTRADMDTMTAAFVAATQRAAAAGFDWLELHAAHGYLLSSF
ITPLTNQRTDEYGGSLANRCRYPLEVFAAMRAVWPADKPFSVRISAHDWAPGGNTPDDAV
EIARLFKAAGCDLIDVSSGQTTRAAKPVYGRMYQTPFADRVRNEAGILTMAVGAITEADH
ANSIIAAGRADLCAVARPHLADPAWTLHEAAKLQTRAIEWPRPYESGRDQLYREIARQQA
LNTPTP