Protein Info for GFF2814 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Glycerol-3-phosphate ABC transporter, permease protein UgpA (TC 3.A.1.1.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details

Best Hits

KEGG orthology group: K02027, multiple sugar transport system substrate-binding protein (inferred from 88% identity to dac:Daci_1030)

Predicted SEED Role

"Glycerol-3-phosphate ABC transporter, permease protein UgpA (TC 3.A.1.1.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (TC 3.A.1.1.3)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (577 amino acids)

>GFF2814 Glycerol-3-phosphate ABC transporter, permease protein UgpA (TC 3.A.1.1.3) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MKLRHTTLAMAALLAMGALPAWADEAAAKKWIDSEFQPSTLTKAQQAAEMKWFIDAAAKL
KAKGVKEISVVSETITTHEYESKTLAKAFAEITGITVKHDLIQEGDVVEKLQTSMQSGKS
IYDGWISDSDLIGTHYRYGKMMNLTDYMAGKGKEYTNPGLDIKDFIGTSFTTAPDKKLYQ
LPDQQFANLYWFRADLFDRKDLKDKFKAKYGYDLGVPLNWSAYEDIAEFFTNDVKTIDGK
PIYGHMDYGKKDPSLGWRFTDAWLSMAGTADIGIPNGKPVDEWGIRASADGCNPQGASVS
RGGATNSPAAVYALTKYIDWMKKYAPKDATGMTFGEAGPVPAQGQIAQQIFWYTAFTADM
TKPGLPVVNADGTPKWRMAPGPNGPYWKQGMQNGYQDVGSWSFFNGHDENKTAAAWLYAQ
FVTAKTTSLKKTIVGLTPIRESDIQSKAMTDLAPKLGGLVEFYRSPARVAWTPTGTNVPD
YPKLAQLWWQNVAQAVTGEKTPQAAMDNLAEQMDQVMSRLERAGMERCAPKLNPKGDPNK
YLSDKAAPWKKLANEKPKGETIAYDQLLNAWKNGKVR