Protein Info for PS417_14350 in Pseudomonas simiae WCS417

Annotation: multidrug DMT transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 30 to 51 (22 residues), see Phobius details amino acids 58 to 78 (21 residues), see Phobius details amino acids 98 to 130 (33 residues), see Phobius details amino acids 138 to 158 (21 residues), see Phobius details amino acids 170 to 191 (22 residues), see Phobius details amino acids 203 to 225 (23 residues), see Phobius details amino acids 240 to 269 (30 residues), see Phobius details PF00892: EamA" amino acids 144 to 274 (131 residues), 45.2 bits, see alignment E=5.8e-16

Best Hits

KEGG orthology group: None (inferred from 83% identity to pfs:PFLU3331)

Predicted SEED Role

"Permeases of the drug/metabolite transporter (DMT) superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TZQ5 at UniProt or InterPro

Protein Sequence (275 amino acids)

>PS417_14350 multidrug DMT transporter permease (Pseudomonas simiae WCS417)
MPFPIVILVLFAALLHASWNALLRVGADRLWSMTVMCLSVALVSIGVALYLPAPAAASWP
YAALSGVLHVGYNLFLVRSYKVGDLGQTYPIARGSSPILITLFALAFAGETLSTSALFGI
ALVSGGIISLAFRQRRLAVPSLPYALGTGFFIAAYSVTDGVGARLSGAPMAYTAWMCALW
GVLMPLVYMGLRGARSLFAPRPGLIPALMGGLVSLLAYGIVIYAMSESPMGSVSALRETS
VLFAALIGYFFLGEALTVRKVLACAVIAAGTMLIG