Protein Info for GFF2801 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 PF02016: Peptidase_S66" amino acids 5 to 126 (122 residues), 79.7 bits, see alignment E=2.1e-26 PF17676: Peptidase_S66C" amino acids 169 to 284 (116 residues), 109.2 bits, see alignment E=2e-35

Best Hits

Swiss-Prot: 81% identical to LDCA_ECO57: Murein tetrapeptide carboxypeptidase (ldcA) from Escherichia coli O157:H7

KEGG orthology group: K01297, muramoyltetrapeptide carboxypeptidase [EC: 3.4.17.13] (inferred from 98% identity to sec:SC1793)

MetaCyc: 80% identical to murein tetrapeptide carboxypeptidase (Escherichia coli K-12 substr. MG1655)
Muramoyltetrapeptide carboxypeptidase. [EC: 3.4.17.13]; RXN0-2061 [EC: 3.4.17.13]

Predicted SEED Role

"Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13)" (EC 3.4.17.13)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.17.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (304 amino acids)

>GFF2801 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MSLFHLIAPSGYCINQQAALRGVQRLTDAGHQVENDEVIRRRFQRFAGTDAERLADVNSL
ASLTSPDTIVMPVRGGYGASRLLDRIDWQALASRQQRDPLLICGHSDFTAIQAGLLAQAN
VITFSGPMLAANFGAETLNTFTEQHFWLALRKAQFTVEWQGDGPQCDAQGTLWGGNLAML
ISLIGTPWMPTIDKGILVLEDVNEHPFRVERMLLQLEYAGILNRQSAIVLGSFSGAAPNE
YDAGYSLESVYAFLRSRLSVPLITGLDFGHEQRTVTLPIGANAMLKNTRQGTQLTLSGHP
TLQL