Protein Info for GFF2800 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Membrane-bound lytic murein transglycosylase E (EC 3.2.1.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01464: SLT
  • amino acids 43 to 168 (126 residues), 96.7 bits, E=3.5e-32

Best Hits

Swiss-Prot: 100% identical to EMTA_SALEP: Endo-type membrane-bound lytic murein transglycosylase A (emtA) from Salmonella enteritidis PT4 (strain P125109)

KEGG orthology group: K08308, membrane-bound lytic murein transglycosylase E [EC: 3.2.1.-] (inferred from 100% identity to spt:SPA1074)

MetaCyc: 90% identical to lytic murein transglycosylase E (Escherichia coli K-12 substr. MG1655)
4.2.2.f [EC: 4.2.2.f]; 4.2.2.f [EC: 4.2.2.f]

Predicted SEED Role

"Membrane-bound lytic murein transglycosylase E (EC 3.2.1.-)" (EC 3.2.1.-)

MetaCyc Pathways

• peptidoglycan recycling I (14/14 steps found)
• peptidoglycan recycling II (7/10 steps found)

KEGG Metabolic Maps

• Ascorbate and aldarate metabolism
• Glycosaminoglycan degradation
• Nucleotide sugars metabolism
• Ubiquinone and menaquinone biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.- or 4.2.2.f

Protein Sequence (203 amino acids)

>GFF2800 Membrane-bound lytic murein transglycosylase E (EC 3.2.1.-) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
VKLRWFAFLVVILAGCSSKQDYRNPPWNAEVPVKRAMQWMPISEKAGAAWGVDPHLITAI
IAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWRGEPTTSELKNPERNISMGAAY
LSILENGPLAGIKDPQVMQYALVVSYANGAGALLRTFSSDRKKAIEKINDLDADEFFEHV
VDNHPAPQAPRYIWKLQQALDAM