Protein Info for GFF2798 in Xanthobacter sp. DMC5

Annotation: Proline/betaine transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 transmembrane" amino acids 23 to 47 (25 residues), see Phobius details amino acids 60 to 85 (26 residues), see Phobius details amino acids 95 to 113 (19 residues), see Phobius details amino acids 119 to 142 (24 residues), see Phobius details amino acids 158 to 182 (25 residues), see Phobius details amino acids 194 to 213 (20 residues), see Phobius details amino acids 246 to 270 (25 residues), see Phobius details amino acids 282 to 304 (23 residues), see Phobius details amino acids 311 to 332 (22 residues), see Phobius details amino acids 338 to 363 (26 residues), see Phobius details amino acids 375 to 397 (23 residues), see Phobius details amino acids 405 to 424 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 24 to 230 (207 residues), 81 bits, see alignment E=8.9e-27 PF07690: MFS_1" amino acids 29 to 388 (360 residues), 93.2 bits, see alignment E=1.6e-30

Best Hits

Swiss-Prot: 31% identical to PROP_STAEQ: Putative proline/betaine transporter (proP) from Staphylococcus epidermidis (strain ATCC 35984 / RP62A)

KEGG orthology group: None (inferred from 90% identity to xau:Xaut_0930)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (434 amino acids)

>GFF2798 Proline/betaine transporter (Xanthobacter sp. DMC5)
MTHATYPLSGQATPSLNKAQWRIIFLASLGGSLEFYDFIIYGIFVQYISAQFFPANDPYV
SLILSFSVLALGFLARPFGGAVLGILGDRYGRRPVFIGSLGLTTLATIAIGLLPNYQSWG
IAAPLLLVAFRLVQGICLGGELPGAVTYAVEAAPARAGLACGFIIFCVNVGVLIATLVNL
GIQYALPPQDVADYGWRIAFLLGGVIGLVSFALRRKLEESPEFVNLHGKATRHPLRELMR
HHGRSVLVAAGVAAIIAGFNGMLYGFVPAFLVKTLHYPAPDVALAMTVALVVSSVGLILA
GWAGDFVPGRLILRVGSLGMVVVVVPLFALMANHGASIVLVLSLLSLVFSLASGIWPSML
AGLFPTQVRFTGIALSYNVSVTLLSGFAPLAATALIAQTGMNSAPALYIAASAALTFWCS
FLIPARSASALPPA