Protein Info for GFF2798 in Variovorax sp. SCN45

Annotation: Molybdopterin molybdenumtransferase (EC 2.10.1.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 412 PF03453: MoeA_N" amino acids 1 to 167 (167 residues), 155.6 bits, see alignment E=1.4e-49 TIGR00177: molybdenum cofactor synthesis domain" amino acids 177 to 323 (147 residues), 96.7 bits, see alignment E=6.3e-32 PF00994: MoCF_biosynth" amino acids 180 to 325 (146 residues), 114.5 bits, see alignment E=5.2e-37 PF03454: MoeA_C" amino acids 341 to 407 (67 residues), 43.6 bits, see alignment E=4.1e-15

Best Hits

KEGG orthology group: K03750, molybdopterin biosynthesis protein MoeA (inferred from 92% identity to vpe:Varpa_2096)

Predicted SEED Role

"Molybdopterin biosynthesis protein MoeA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (412 amino acids)

>GFF2798 Molybdopterin molybdenumtransferase (EC 2.10.1.1) (Variovorax sp. SCN45)
MPLDEAIAVLLAKAQPTALPNESVGTFDADGRVLAQDLVSGLTVPPRDNSAMDGYAVRVA
DCAAPGAELKVAQRIPAGTVGTPLAAGTAARIFTGAQIPEGADAVVMQEDTTATPQEGGL
GSVRIAIVPAAGQWIRRAGEDVASGDVVLKKGERLTPAALGLAASIGFHKLQVARRPRVA
MLSTGDELVMPGEVAPDAMKPGAIYNSNRFFMRALLHRLGCEVNDLGIVPDNREATIAAL
RDAAETSDLIITTGGVSVGEEDHIRAALQSLGELQLWSLSMKPGKPFAYGSIARGNGQGA
CHVTGLPGNPVSSFLTFLMLVRPFLLTLQGATRVAPEPVKMRADFDWPRADKRREFLRAR
RNAAGGLELFGNQSSGVLTSMVWGDGVVDNPAGQTIKSGDIVDFIPFASLLG