Protein Info for PS417_14215 in Pseudomonas simiae WCS417

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 175 PF05163: DinB" amino acids 5 to 173 (169 residues), 97.5 bits, see alignment E=8.7e-32 PF12867: DinB_2" amino acids 19 to 154 (136 residues), 32.5 bits, see alignment E=1.2e-11

Best Hits

KEGG orthology group: None (inferred from 86% identity to pfs:PFLU2952)

Predicted SEED Role

"DinB family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TXR7 at UniProt or InterPro

Protein Sequence (175 amino acids)

>PS417_14215 diguanylate cyclase (Pseudomonas simiae WCS417)
MNRTEHIALMANYNQWMNRKLYDAAQTLTDAELAMDRQAFFGSILGTLNHLVLGDTVWLK
RFAQHPAGFTALAPLHVIATPADLKQLAFADIRELAAHRTWLDQLIVDWSHSVQEPDLDH
RLHYRNMRGVSADKDFFSLLVHFFNHQTHHRGQATTLLTQAGLDVGTTDLLALID