Protein Info for GFF2784 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 167 to 187 (21 residues), see Phobius details PF05227: CHASE3" amino acids 33 to 158 (126 residues), 98 bits, see alignment E=6.9e-32 PF07730: HisKA_3" amino acids 236 to 303 (68 residues), 37.5 bits, see alignment E=4.4e-13 PF02518: HATPase_c" amino acids 341 to 431 (91 residues), 40.8 bits, see alignment E=4e-14

Best Hits

KEGG orthology group: None (inferred from 41% identity to pol:Bpro_0880)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (446 amino acids)

>GFF2784 Sensor histidine kinase (Hydrogenophaga sp. GW460-11-11-14-LB1)
LAVLLALGVLAGAEWTYQRALGAMAGLGARDTARTAIQTVMRRLLDMETAQRGYLLTGRP
QYLDPYQAAETDIAHAISRLREHYRNDTDLLRLVDSLQERAGEKISEVTETITLYNAGSH
AAWHGLMLTDIGREKMEGVRRAADVLLVTEERRLAIERAAIYRTLGAGRIGVYALTLLSL
LAYVFFLRKNAALQNSQIEHARHLQVERDSLESQVRLRTEELAQLNLGLQEMRDGERSGL
ARALHDELGALLTAAKLDLTRLRHALHTTDPEVTERLRHLSASLDEGIGMKRRIMEELMP
SALHNLGLQAALEQRATEFERHTGVNIDLAFMPVTLTAPTEQALFAVVQGALSNIERHAS
ATQVSLRLAQEGVHALVEVQDNGRGFADRSGTTSASGLKNLRHRIESLGGQFSVHSVPGS
GTRIQARLPMRQRELDSGHPHATNPP