Protein Info for GFF2783 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 187 to 206 (20 residues), see Phobius details PF05227: CHASE3" amino acids 50 to 163 (114 residues), 42 bits, see alignment E=1.3e-14 PF07730: HisKA_3" amino acids 248 to 314 (67 residues), 49 bits, see alignment E=1.1e-16 PF02518: HATPase_c" amino acids 352 to 441 (90 residues), 50.7 bits, see alignment E=3.4e-17

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (450 amino acids)

>GFF2783 Sensor histidine kinase (Hydrogenophaga sp. GW460-11-11-14-LB1)
MMIKSSIERVARNRFGMPIILALALIMVVVNEASYQHSRSTLMQGITLSDARQQAARTLQ
ALTDAEVAVRAFMLSAQQADLANYREAINEMEGVQQDAFKRLEELDPKRTVSVSDVRKRI
EERTATLNQWVNMIEQGRRTDAQTLAVSDQGRLRYAELRQEFEFVLERAAAIQKTARVSL
FDAMMINRLAIHLLVLVAWVALILFMRQLRESDRRQSEEHQRLATQVALRTTALRNLAGH
HVNAREDERGRVARELHDEMGGLLTAMKLDIARLRRVPALPAPALERLASIEQRLTEGIA
VKRRIIEHLRPSSLDQLGLIPALDMLCQDAASRMGIAVDTQFSPVQLGKDAELTVYRLVQ
ESLTNVQKYAHARRVSVELAQAGDTVRVSVRDDGKGFDIDSVPAGHHGLLGMRVRVESHS
GQLSVHSAMHQGTRVEAELPAHPVEKADLA