Protein Info for PS417_14195 in Pseudomonas simiae WCS417

Annotation: magnesium ABC transporter ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 904 transmembrane" amino acids 84 to 103 (20 residues), see Phobius details amino acids 114 to 131 (18 residues), see Phobius details amino acids 291 to 311 (21 residues), see Phobius details amino acids 320 to 344 (25 residues), see Phobius details amino acids 712 to 737 (26 residues), see Phobius details amino acids 773 to 796 (24 residues), see Phobius details amino acids 808 to 826 (19 residues), see Phobius details amino acids 838 to 858 (21 residues), see Phobius details amino acids 874 to 892 (19 residues), see Phobius details TIGR01524: magnesium-translocating P-type ATPase" amino acids 19 to 903 (885 residues), 1388.5 bits, see alignment E=0 PF00690: Cation_ATPase_N" amino acids 30 to 95 (66 residues), 40.2 bits, see alignment 5.5e-14 PF00122: E1-E2_ATPase" amino acids 147 to 354 (208 residues), 136 bits, see alignment E=2.6e-43 TIGR01494: HAD ATPase, P-type, family IC" amino acids 269 to 394 (126 residues), 73.2 bits, see alignment E=1.5e-24 amino acids 617 to 733 (117 residues), 94.7 bits, see alignment E=4.4e-31 PF00702: Hydrolase" amino acids 370 to 658 (289 residues), 51.6 bits, see alignment E=4.1e-17 PF13246: Cation_ATPase" amino acids 418 to 484 (67 residues), 25.5 bits, see alignment 2.7e-09 PF00689: Cation_ATPase_C" amino acids 727 to 895 (169 residues), 77.7 bits, see alignment E=2.5e-25

Best Hits

KEGG orthology group: K01531, Mg2+-importing ATPase [EC: 3.6.3.2] (inferred from 74% identity to bmf:BAB2_0036)

Predicted SEED Role

"Mg(2+) transport ATPase, P-type (EC 3.6.3.2)" (EC 3.6.3.2)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.2

Use Curated BLAST to search for 3.6.3.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U701 at UniProt or InterPro

Protein Sequence (904 amino acids)

>PS417_14195 magnesium ABC transporter ATPase (Pseudomonas simiae WCS417)
MSAVKNTPLHKKNGTDADTKLSMRAAREAHNGLSATLANVRATQDGLTELDACGRLQREG
YNEVAHDKPPHAIVQFLQALNNPFIYVLLTLGGISFFTDCWLPMQEGEEADPTKVIIIMT
MVLLSSLLRFWQEHRSAKSAEALKAMVRTTATVLRREQVGSPPTLREVPMRELVAGDIVQ
LSAGDMIPADIRLIESRDLFISQAVLTGEALPVEKYDTLGNVTQKSAGPVTADQGNLLDL
PNICFMGTNVVSGRAKAVVVATGPRTYFGSLAKAIVGSRVQTAFDRGVNSVSWLLIRFML
VMVPIVFLLNGFSKGDWGDAFLFALAVAVGLTPEMLPMIVSANLAKGATAMAKRKVVVKR
LNAIQNFGSMDVLCTDKTGTLTQDKIILEHHVNAFGQRDDAVLSLAWLNSHHQSGMKNLM
DQAVVEFSEQNPKFKVPFAYSKIDELPFDFVRRRLSIVVKDAADDQLLVCKGAVEEMLSI
SSHVMEAGAAVPLDERRREELLAIANDYNEDGFRVLVVATRHIPKSMARQQYTTADERNL
VIQGFLTFLDPPKETAGPAIAALQQIGVAIKVLTGDNAVVTSKICRQVGLEPGQPLLGAE
IEAMDDATLLRRVEERTVFAKLTPLQKSRVLKALQANGHTVGFLGDGINDAPALRDADVG
ISVDTATDIAKESADIILLEKSLMVLEEGVLKGRETFGNIMKYLNMTASSNFGNVFSVLV
ASAFIPFLPMLSIHLLLQNLMYDISQLALPWDKMDKEYLAKPRKWDAKNIGRFMIWIGPT
SSIFDITTFALMWFVFAANSVEVQTLFQSGWFIEGLLSQTLVVHMLRTRKIPFFQSTAAW
PVLMMTCVVIVLGIYVPFSPLGTLVGLQPLPMAYFPWLVGTLISYCCVAQLMKTIYIRRF
KQWY