Protein Info for GFF2782 in Pseudomonas sp. DMC3

Annotation: putative MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 transmembrane" amino acids 21 to 37 (17 residues), see Phobius details amino acids 44 to 66 (23 residues), see Phobius details amino acids 76 to 98 (23 residues), see Phobius details amino acids 107 to 129 (23 residues), see Phobius details amino acids 142 to 161 (20 residues), see Phobius details amino acids 167 to 186 (20 residues), see Phobius details amino acids 218 to 239 (22 residues), see Phobius details amino acids 251 to 273 (23 residues), see Phobius details amino acids 285 to 302 (18 residues), see Phobius details amino acids 308 to 330 (23 residues), see Phobius details amino acids 342 to 364 (23 residues), see Phobius details amino acids 372 to 394 (23 residues), see Phobius details PF12832: MFS_1_like" amino acids 18 to 377 (360 residues), 67.1 bits, see alignment E=1.5e-22 PF07690: MFS_1" amino acids 18 to 239 (222 residues), 98.9 bits, see alignment E=2.9e-32 amino acids 223 to 400 (178 residues), 64.2 bits, see alignment E=1e-21

Best Hits

Swiss-Prot: 57% identical to Y2456_MYCTU: Uncharacterized MFS-type transporter Rv2456c (Rv2456c) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: None (inferred from 83% identity to pfo:Pfl01_3356)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (413 amino acids)

>GFF2782 putative MFS-type transporter (Pseudomonas sp. DMC3)
VISHLDRRNNRSLDSLNFFLADVRDGLGPYLAIYLLAVHHWDPASIGVVMTLAGIAALVT
QTPAGALVDSSRAKRALIIIAALLVTVSCLLLPFISSFSLVALTQALSAAAASIFAPAIS
AITLGITGPRAFTRRTGRNETFNHAGNACAALLAGLFAYLFGPVAVFYLMAVMALASVIA
VLFVSAEAIDHDVARGLQPGDQSHQPSGFKVLLSNRPLLMFALCCALFHLANAAMLPLVS
QKLAQANLHMATPLTSACIVAAQLVMVPMALLAGAKADVWGRKPLLLAGFLILPLRGLLY
TFSDDPYWLVAVQLLDGVGAGLFGALFPVMVKDLTLGSGHFNVSLGALTTAFGLGAALSN
GLAGFVVEAAGYSAAFLTLAGIAAAAFLLLLIAVPETLQRTEQFESAAVVGQT