Protein Info for PS417_14165 in Pseudomonas simiae WCS417

Annotation: ArsR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 118 PF01022: HTH_5" amino acids 24 to 61 (38 residues), 46.6 bits, see alignment E=1.2e-16

Best Hits

Swiss-Prot: 63% identical to ARSR1_PSEPK: Arsenic resistance transcriptional regulator ArsR1 (arsR1) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: None (inferred from 68% identity to pba:PSEBR_gl76)

Predicted SEED Role

"Arsenical resistance operon repressor" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UCA7 at UniProt or InterPro

Protein Sequence (118 amino acids)

>PS417_14165 ArsR family transcriptional regulator (Pseudomonas simiae WCS417)
MSDAISPPTLFKCLADATRARLTLLILREGELCVCELIHALDDSQPKISRHLAQLRSCGL
LLDRRQGQWIYYRINPALPEWVTQVLHITQQANQPWLHSDAQRLDAMGDRPQRASTCC