Protein Info for GFF2766 in Xanthobacter sp. DMC5

Annotation: 3-methylitaconate isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 371 PF04303: PrpF" amino acids 1 to 360 (360 residues), 341.4 bits, see alignment E=3e-106

Best Hits

Swiss-Prot: 38% identical to PRPF_SHEON: 2-methyl-aconitate isomerase (prpF) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K09788, hypothetical protein (inferred from 59% identity to mrd:Mrad2831_4989)

Predicted SEED Role

"Uncharacterized protein Bsu YraM"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (371 amino acids)

>GFF2766 3-methylitaconate isomerase (Xanthobacter sp. DMC5)
MRGGTSKALMFHARDLPPDRTTWDELFAAAMGSPDPYGRQLDGMGGGLSSLSKVCVVGPS
QRPDADVDYTFAQVAIGAPRVDYSGNCGNMTSAVGPFAVDERMVAPPEDGEARVRIFNTN
TSKLIHATFPVEDGCARFDGDLAIPGVSGTGAPIRLDFIDPGGASTGRLLPTGAVRDVLD
VPGLGRLEVSMLDAANAAVFVRAEDVGLTGHEAPQELDTRADILARLDAIRCAASVAMGI
APDIEAARRIPVIPFICFVASAEGDTDGDFVIRAISNGQPHRALPLTISLCAAAAAQMDG
SVVAECRRPERSAGPIRLVMPAGVLTVDADVVRTPDGWQVRSGSFYRTARRLFDGRVWIP
GHIYRLAEGRA